What is the primary use of proton pump inhibitors (PPIs)?

The primary use of proton pump inhibitors (PPIs) is to significantly reduce gastric acid production. This action makes them particularly effective in treating conditions such as gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome. By inhibiting the proton pump in the stomach lining, PPIs decrease the secretion of gastric acid, which helps alleviate symptoms associated with excess acid, such as heartburn and discomfort.

PPIs are often prescribed to prevent damage to the esophagus and promote healing in patients with GERD, as well as to provide relief from the painful symptoms that result from acid reflux. Additionally, their role in promoting healing of peptic ulcers by creating a less acidic environment in the stomach is well-established in clinical practices.